Description
Indications for the use of Xenical are obesity in adults, as well as weight maintenance after weight loss. During the period of drug therapy, it is recommended to follow a strict diet with restrictions on fats and physical activity.
Xenical does not suppress appetite but reduces the energy balance of the diet. Remember that 1 g of fat provides as much as 9 kcal, and a gram of protein and carbohydrates provides 4 kcal each. When there is a caloric deficit, the body begins to use up fat deposits and so weight loss occurs.
Orlistat: mechanism of action
Orlistat (Mexico) helps in the fight against obesity due to its main property – inhibition of gastric and pancreatic lipases. This property of the drug disturbs the normal breakdown of dietary fats, and they are absorbed from the gastrointestinal tract worse. If the drug is taken systematically, it is possible to achieve weight reduction.
The drug is practically not absorbed in the stomach. Minimal absorption occurs in the intestine. About 97% of the dose taken is excreted with the feces. Only 2% of the drug taken is excreted with the urine.
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Orlistat: side effects
Orlistat 120 mg may have side effects that you should familiarize yourself with before taking it. On the side of the immune system, an allergic reaction occurs. Its mild manifestations are rash and itching. Severe manifestations include respiratory disorders, manifested in pulmonary edema, and bronchospasm. The most severe reaction is anaphylactic shock.
More often the drug disrupts the normal operation of the gastrointestinal tract. The following undesirable reactions may occur:
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oily discharge from the rectum;
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diarrhea;
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pain in the stomach;
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flatulence;
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minor bleeding;
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diverticulitis;
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pancreatitis.
Increased activity of hepatic transaminases, hepatitis, the occurrence of kidney stones, hyperoxaluria, and oxalate nephropathy are reactions that occur frequently. The frequency of these adverse reactions has not been studied in detail. Side effects with unspecified frequency include bullous rashes.
Orlistat: weight loss
Before taking the drug, you need to establish and organize a low-calorie diet for the normal functioning of the body. In the diet, there should be 30% of fats, which should be moderately distributed in all meals. Unwanted side effects such as diarrhea can occur due to the increase in fats in the diet. Therefore, without a balanced diet, the drug will not be effective. The diet should include plenty of fruits and vegetables.
Diarrhea can lead to a decrease in the effectiveness of oral contraceptives, so another method of contraception should be used in addition.
Orlistat over-the-counter
Orlistat is sold at an affordable cost in our pharmacy. You can buy Orlistat online over the counter. We will provide the necessary consultation of a medical professional so that you can take the product with safety for your health. Shipment is made by postal services.
Orlistat: interactions
Xenical Orlistat may affect blood thinning, so it should not be taken with warfarin and other indirect-acting anticoagulants. The drug should not be taken simultaneously with Cyclosporine or Sitagliptin. Orlistat pills should not be taken concomitantly with Cyclosporine because of reduced efficiency.
The active substance of the drug decreases the blood plasma concentration of amiodarone, such a combination is possible only after the permission of the doctor and drawing up an individual treatment regimen. The drug impairs the absorption of fat-soluble vitamins A, D, E, K, and beta-carotene. Multivitamins should be taken after 2 hours of taking Orlistat or before going to bed. The drug may reduce the absorption of Levothyroxine and Iodine, which are in iodized salt. Therefore, there is a risk of progression of hypothyroidism.
The drug reduces the absorption of drugs against epilepsy, drugs for depression, and neuroleptics.
Contraindications of Orlistat
Orlistat pills should not be taken in cases:
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Individual intolerance to individual components of the drug
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Chronic malabsorption
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Cholestasis
For patients with impaired renal function, the drug is prescribed only after a thorough examination. It can cause oxalate nephropathy. With a severe course, renal failure may occur. Taking Orlistat pills by patients with liver pathologies is possible, but only after strictly recommended doses.
If weakness, fatigue, yellowing of the skin, or changes in the color of the urine occur, you should always consult a doctor. Such symptoms indicate liver dysfunction. The drug against obesity should not be taken by patients under 18 years of age. Also, the medication is contraindicated for pregnant women and during breastfeeding.
Orlistat: price
The price of the Orlistat 120 mg is lower than in other pharmacies. The cost depends on the dosage. The drug in capsule form is cheaper than in tablet form. For more information, ask the consultants. The website shows the price for a single pack of 21 capsules.
Orlistat: dosage
Orlistat 120 mg shouldn’t be taken longer than 6 months. The maximum daily dosage is 180 mg. Depending on the patient’s condition, the doctor may prescribe one tablet a day or divide it into 3 doses of 60 mg. Before starting treatment, it is necessary to undergo a comprehensive diagnosis to determine the correct treatment regimen and avoid adverse reactions.
Xenical side effects
The use of Xenical 120mg may cause side effects for patients. The most common side effects complained of by patients are gastrointestinal disorders (abdominal pain, diarrhea, flatulence); liver failure and, in rare cases, liver damage; irregular menstruation or failure of the cycle; increased fatigue; skin allergic reactions; dental and gum disease.
The instruction on this site is for information purposes only and is not intended for use.
Consult your physician before purchasing Xenical online. If you experience one or more of these side effects, see your doctor. Your doctor will reduce the dosage or split it into several doses, or use an analog product.
Xenical price
Xenical 120mg capsules reduces the amount of fat in your daily diet. You can buy Xenical online at an attractive price on our website.
Xenical weight loss
The drug is used to treat patients who are obese (BMI 30 or higher) or overweight (BMI 28-30) when associated with other risk factors, such as:
- Arterial hypertension
- High cholesterol levels
- Carbohydrate disorders
- Diabetes
For the above-mentioned problems, weight loss can have measurable health effects, for example, in the early stages of type 2 diabetes, it can stabilize blood sugar level without the need for sugar-lowering medications.
Xenical: dosage
The doctor may prescribe 1 tablet 120 mg – 3 times daily for people who are obese or overweight with additional risk factors. For patients with overweight without risk factors, 60 mg (half a tablet) 3 times a day is prescribed.
How to take Xenical for best results?
Once you buy Xenical, you must strictly follow the instructions. Take it before every fat-containing meal. If your meal is skimmed, skip the dose. In order for weight loss to bring the desired results, patients must follow a diet in which about 30% of the energy comes from fat. The diet should be varied, and the daily rate of fats, proteins, and carbohydrates should be distributed according to the dietitian’s recommendations.
Orlistat vs Xenical
Xenical and Orlistat are effective weight loss drugs available on the pharmaceutical market. Let’s look at a comparison table of the two drugs.
Name of medication |
Xenical |
Orlistat |
Side effects |
Hypoglycemia in patients with type 2 diabetes, headache, upper respiratory tract infections, abdominal pain, avitaminosis. |
Liver and biliary tract: hepatitis, cholelithiasis. Skin itching, rash, urticaria, angioedema |
Half-life |
1-2 hours |
1 to 2 hours |
Composition |
Orlistat – 120 mg, microcrystalline cellulose – 93.6 mg, sodium carboxymethyl starch (primogel) – 7.2 mg, povidone K-30 – 12 mg, sodium lauryl sulfate – 7.2 mg. Excipients: talc – 0.24 mg. |
Active ingredient: Orlistat, pellet Substance 50% – 120.00 mg, in terms of orlistat – 60.00 mg. Excipients of the pellet substance: microcrystalline cellulose 49.32 mg, sodium carboxymethyl starch 5.04 mg, sodium lauryl sulfate 3.12 mg, povidone-CZ0 2.52 mg. |
Form |
120 mg capsules |
Solid gelatin capsules 120 mg |
Duration of intake |
Takes a long time – for 6-12 months or more, which allows you to achieve a weight loss of 2 to 6 kg per month. |
No more than three 60 mg capsules of Orlistat can be taken per day. The course of treatment should not exceed 6 months. It is recommended to discuss the results of weight loss with your doctor. |
Both drugs should be combined with a proper diet, and the therapy can be continued for a long period only if it really gives the desired effect.
Xenical in diabetes and hormonal contraception
Patients with diabetes may experience hypoglycemia as a result of treatment with Xenical 120. An endocrinologist should be consulted during therapy.
Because of the high risk of diarrhea, Xenical may reduce the effectiveness of hormonal contraceptive pills used. Therefore, during treatment, it is recommended to extend contraceptive measures, such as the use of condoms.
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